Epilepsy Group

A rapidly growing epilepsy research base covering genetics, neuroimmunology, electrophysiology and clinical is reflected in the annual North East Epilepsy Conference. A particular emphasis is on integrative, translational research.

Principle Investigators

Mark Cunningham
http://www.ncl.ac.uk/ion/staff/profile/mark.cunningham is using high-density microelectrode arrays in human epileptic brain to understand the development of abnormal epileptogenic rhythms and is also addressing the pathogenic mechanisms underlying epilepsy associated with auto-immune encephalitidies.

Andy Trevelyan is an electrophysiology scientist conducting clinical translational work in deciphering exactly what EEGs tell us about the location of seizure activity.


Rhys Thomas Rhys joined Newcastle University from Cardiff University in August 2017. He is an Honorary Consultant in Epilepsy at the Royal Victoria Infirmary. He works with adults with epilepsy and intellectual disability, and also mitochondrial disorders. His research interests include the causes and consequences of epilepsy – primarily the genetic causes of the epilepsies. Rhys was the 2017 Royal College of Physicians Linacre lecturer speaking about the risks and benefits of Sodium Valproate for women of child-bearing age.


Roger Whittaker’s clinical and research interest is in the neurophysiology of mitochondrial diseases. These inherited conditions are associated with an increased risk of epilepsy, peripheral neuropathy, neuromuscular junction abnormalities and myopathy. His interest is in characterising the clinical aspects of these complications, investigating the underlying pathophysiology and in developing techniques to determine which patients are most at risk of developing them. He holds an Honorary Clinical Senior Lecturer position in the Institute of Neuroscience, Newcastle University.




Marcus Kaiser is a computational neuroscientist who is analysing and simulating the spreading of activity in hierarchical clustered networks to understand the spreading of epileptic seizures.


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